Laboratory studies show decreased or absent numbers of nonfunctional T cells, normal or increased levels of B cells, variable hypogammaglobulinemia, and normal NK cells. Some patients have lymphadenopathy and hepatosplenomegaly, whereas others have absence of lymph nodes and lack a thymic shadow. Manifestations may include oral thrush, fever, and failure to thrive. Immunodeficiency-104 (IMD104) is an autosomal recessive disorder characterized by the onset of recurrent infections in early infancy. Immunodeficiency, X-linked, with hyper-IgM Lymphoproliferative syndrome, X-linked, 1 Severe combined immunodeficiency, X-linked Immunodeficiency 34, mycobacteriosis, X-linkedĬombined immunodeficiency, X-linked, moderate Immunodeficiency 98 with autoinflammation, X-linked Immunodeficiency 74, COVID19-related, X-linked Immunodeficiency 73B with defective neutrophil chemotaxis and lymphopenia ?Immunodeficiency 73C with defective neutrophil chemotaxis and hypogammaglobulinemia Immunodeficiency 73A with defective neutrophil chemotaxix and leukocytosis Immunodeficiency 63 with lymphoproliferation and autoimmunity Immunodeficiency 106, susceptibility to viral infections Immunodeficiency 91 and hyperinflammation ?Immunodeficiency 99 with hypogammaglobulinemia and autoimmune cytopenias ?Immunodeficiency 101 (varicella zoster virus-specific) Immunodeficiency 32A, mycobacteriosis, autosomal dominant Immunodeficiency 32B, monocyte and dendritic cell deficiency, autosomal recessive Immunodeficiency 65, susceptibility to viral infections Immunodeficiency 7, TCR-alpha/beta deficient Immunodeficiency 78 with autoimmunity and developmental delay Immunodeficiency 100 with pulmonary alveolar proteinosis and hypogammaglobulinemia Immunodeficiency 72 with autoinflammation Immunodeficiency 90 with encephalopathy, functional hyposplenia, and hepatic dysfunction Immunodeficiency 80 with or without cardiomyopathy Immunodeficiency 41 with lymphoproliferation and autoimmunity Immunodeficiency 103, susceptibility to fungal infection Immunodeficiency 82 with systemic inflammation Immunodeficiency 26, with or without neurologic abnormalities Immunodeficiency 97 with autoinflammation Immunodeficiency 71 with inflammatory disease and congenital thrombocytopenia Immunodeficiency 11B with atopic dermatitis Immunodeficiency 27A, mycobacteriosis, AR Immunodeficiency 27B, mycobacteriosis, AD Immunodeficiency 57 with autoinflammation Immunodeficiency 93 and hypertrophic cardiomyopathy ?Immunodeficiency 94 with autoinflammation and dysmorphic facies Immunodeficiency 31A, mycobacteriosis, autosomal dominant Immunodeficiency 31B, mycobacterial and viral infections, autosomal recessive Immunodeficiency 31C, chronic mucocutaneous candidiasis, autosomal dominant Immunodeficiency 14B, autosomal recessive

Severe combined immunodeficiency scid